Genome Sequence of Enterococcus faecium Strain ICIS 96 Demonstrating Intermicrobial Antagonism Associated with Bacteriocin Production

Tatiana M Pashkova; Alexey S Vasilchenko; Yuriy A Khlopko; Elena E Kochkina; Olga L Kartashova; Maria V Sycheva

doi:10.1128/genomeA.00126-18

Genome Sequence of Enterococcus faecium Strain ICIS 96 Demonstrating Intermicrobial Antagonism Associated with Bacteriocin Production

Genome Announc. 2018 Mar 8;6(10):e00126-18. doi: 10.1128/genomeA.00126-18.

Authors

Tatiana M Pashkova^{1

2}, Alexey S Vasilchenko³, Yuriy A Khlopko^{1

2}, Elena E Kochkina², Olga L Kartashova^{1

2}, Maria V Sycheva^{4

2}

Affiliations

¹ Institute of Cellular and Intracellular Symbiosis, RAS, Orenburg, Russian Federation.
² Orenburg State Agrarian University, Orenburg, Russian Federation.
³ Tyumen State University, Tyumen, Russian Federation.
⁴ Institute of Cellular and Intracellular Symbiosis, RAS, Orenburg, Russian Federation sycheva_maria@mail.ru.

Abstract

We report here the complete genome sequence of Enterococcus faecium strain ICIS 96, which was isolated from the feces of a horse. Bacteriological characterization of strain ICIS 96 revealed the absence of pathogenicity factors, while its spectrum of antagonistic activity was found to be broad, having activities associated with both Gram-positive and Gram-negative bacteria. Analysis of the E. faecium ICIS 96 genome revealed five genes associated with antimicrobial activity (enterocin [ent] A, ent B, lactobin A/cerein 7b, and ent L50 A/B). No genes that correlate with human pathogenicity were identified.