Clinical and biochemical approach to predicting post-pregnancy metabolic decompensation

Diabetes Res Clin Pract. 2018 Nov:145:178-183. doi: 10.1016/j.diabres.2018.02.035. Epub 2018 Mar 6.

Abstract

The prevalence of gestational diabetes in the developed world is increased and parallels that of obesity. Apart from the maternal and fetal complications occurring during pregnancy, GDM is characterized by a high subsequent risk of type 2 diabetes, metabolic syndrome, and cardiovascular disease. In this paper, we outline the different factors to consider in assessing the future risk of diabetes developing in women with a history of GDM. Looking at the modifiable risk factors, it is worth noting that promoting a healthy diet and lifestyle before (physical activity), during and after pregnancy (breast feeding) in women of fertile age are fundamental to the success of efforts to reduce the burden of diabetes in these young people.

Keywords: Biochemical markers; Clinical risk factors; Gestational diabetes; Postpartum diabetes development.

Publication types

  • Review

MeSH terms

  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetes Mellitus, Type 2 / prevention & control*
  • Exercise*
  • Female
  • Humans
  • Italy / epidemiology
  • Life Style*
  • Metabolic Syndrome / epidemiology
  • Metabolic Syndrome / prevention & control*
  • Postpartum Period*
  • Pregnancy
  • Prevalence