Reliability of 3D arterial spin labeling MR perfusion measurements: The effects of imaging parameters, scanner model, and field strength

Clin Imaging. 2018 Nov-Dec:52:23-27. doi: 10.1016/j.clinimag.2018.02.016. Epub 2018 Mar 22.

Abstract

The aim of this study was to investigate the reliability of cerebral blood flow (CBF) measurements obtained by 3D pseudo-continuous arterial spin labeling (pCASL) imaging according to imaging parameters, scanner model, and field strength. We acquired 3D pCASL images in 12 healthy volunteers using four different scanners: two 3.0 T scanners and two 1.5 T scanners. Reliability was evaluated using intraclass correlation coefficient. Our results indicate that the influence of the post-labeling delay and scanner model on CBF measurements should be taken into consideration. If two scanners of the same model are used, scannerdependent differences may be small.

Keywords: Arterial spin labeling; Field strength; Imaging parameter; Reliability; Scanner.

Publication types

  • Validation Study

MeSH terms

  • Adult
  • Arteries / diagnostic imaging*
  • Cerebrovascular Circulation*
  • Female
  • Healthy Volunteers
  • Humans
  • Imaging, Three-Dimensional
  • Magnetic Resonance Angiography / instrumentation
  • Magnetic Resonance Angiography / methods*
  • Male
  • Perfusion
  • Reproducibility of Results
  • Spin Labels*
  • Vascular Surgical Procedures
  • Young Adult

Substances

  • Spin Labels