The intestinal microbiome influences checkpoint blockade

Nat Med. 2018 Mar 6;24(3):254-255. doi: 10.1038/nm.4511.

Abstract

Studies in metastatic melanoma, non-small-cell lung carcinoma and renal cell carcinoma indicate certain bacteria within the gut microbiota enhance clinical responses to checkpoint blockade.

MeSH terms

  • Animals
  • Bacteria / metabolism
  • Biodiversity
  • Feces / microbiology
  • Gastrointestinal Microbiome*
  • Humans
  • Immune System / metabolism
  • Immunotherapy*
  • Mice