Abstract
The HCV 5'UTR, Core/E1, and NS5B regions of samples from fifty patients infected with the hepatitis C virus (HCV) were analyzed. Seventeen patients were identified with genotype (GT) 1b, eleven with GT-1a, nine with GT-2b and four with GT-3a. Two rare subtypes were detected: GT-2j in two patients and GT-2r in one patient. Three patients had mixed infections: one with GT-2k + 2j and two with GT-1b + 2b. This work identifies HCV GTs, 2j, 2k, and 2r for the first time in Mexico.
Keywords:
epidemiology; evolution; genetic variability; hepatitis C virus; virus classification.
© 2018 Wiley Periodicals, Inc.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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5' Untranslated Regions / genetics
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Adult
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Cities
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Female
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Genetic Variation*
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Genotype*
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Genotyping Techniques
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Hepacivirus / classification*
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Hepacivirus / genetics*
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Hepacivirus / isolation & purification
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Hepatitis C / virology*
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Humans
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Male
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Mexico
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Middle Aged
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Sequence Analysis, DNA
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Viral Core Proteins / genetics
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Viral Envelope Proteins / genetics
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Viral Nonstructural Proteins / genetics
Substances
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5' Untranslated Regions
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E1 protein, Hepatitis C virus
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Viral Core Proteins
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Viral Envelope Proteins
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Viral Nonstructural Proteins
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nucleocapsid protein, Hepatitis C virus
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NS-5 protein, hepatitis C virus