[Bio-adhesive drug delivery system and its application in traditional Chinese medicine]

Zhongguo Zhong Yao Za Zhi. 2017 Dec;42(24):4687-4693. doi: 10.19540/j.cnki.cjcmm.20171026.001.
[Article in Chinese]

Abstract

Bio-adhesive drug delivery system (BDDS) is a novel drug delivery system, which can prolong the retention time of the preparation, improve the stability of the drug, and improve the mucosa absorption and the targeting of the drug. With the development of polymer materials over the past 30 years, BDDS made a great progress. This paper reviews the muco-adhesion theory, adhesive materials, and methods to evaluate muco-adhesive properties and applications in traditional Chinese medicine according to domestic and foreign literatures, in order to provide new ideas for further studies.

Keywords: adhesive material; bio-adhesive drug delivery system; evaluation method; muco-adhesion theory.

Publication types

  • Review

MeSH terms

  • Adhesives*
  • Drug Delivery Systems*
  • Medicine, Chinese Traditional
  • Pharmaceutical Preparations / administration & dosage*
  • Polymers

Substances

  • Adhesives
  • Pharmaceutical Preparations
  • Polymers