Progressive severe B cell and NK cell deficiency with T cell senescence in adult CD40L deficiency

Clin Immunol. 2018 May:190:11-14. doi: 10.1016/j.clim.2018.02.008. Epub 2018 Feb 21.
No abstract available

Keywords: B cells; CD4 T cells; CD40 ligand deficiency; Natural killer (NK) cells; T cell senescence.

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • B-Lymphocytes / immunology*
  • B-Lymphocytes / metabolism
  • CD4-Positive T-Lymphocytes / cytology
  • CD4-Positive T-Lymphocytes / immunology*
  • CD4-Positive T-Lymphocytes / metabolism
  • CD40 Ligand / deficiency
  • CD40 Ligand / immunology*
  • Cellular Senescence / immunology*
  • Humans
  • Killer Cells, Natural / immunology*
  • Killer Cells, Natural / metabolism
  • Lymphocyte Activation / immunology
  • Lymphocyte Count
  • Male

Substances

  • CD40 Ligand