IWTomics: testing high-resolution sequence-based 'Omics' data at multiple locations and scales

Bioinformatics. 2018 Jul 1;34(13):2289-2291. doi: 10.1093/bioinformatics/bty090.

Abstract

Summary: With increased generation of high-resolution sequence-based 'Omics' data, detecting statistically significant effects at different genomic locations and scales has become key to addressing several scientific questions. IWTomics is an R/Bioconductor package (integrated in Galaxy) that, exploiting sophisticated Functional Data Analysis techniques (i.e. statistical techniques that deal with the analysis of curves), allows users to pre-process, visualize and test these data at multiple locations and scales. The package provides a friendly, flexible and complete workflow that can be employed in many genomic and epigenomic applications.

Availability and implementation: IWTomics is freely available at the Bioconductor website (http://bioconductor.org/packages/IWTomics) and on the main Galaxy instance (https://usegalaxy.org/).

Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Databases, Factual*
  • Genome
  • Genomics / methods*
  • Sequence Analysis
  • Software*
  • Workflow