Abstract
We determined the accuracy of the new Xpert MTB/RIF Ultra assay for diagnosis of pulmonary tuberculosis in children, using banked-induced sputum. Sensitivity and specificity were 75.3% and 96.9%, respectively, compared with a culture result from the same specimen. Of those children with microbiologically confirmed tuberculosis (positive Xpert, Ultra or culture), Xpert detected 63.2%, Ultra 73.7% and culture 82.9%.
Publication types
-
Research Support, N.I.H., Extramural
-
Research Support, Non-U.S. Gov't
-
Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
-
Adolescent
-
Child
-
Child, Preschool
-
Colony Count, Microbial
-
Female
-
Humans
-
Male
-
Molecular Diagnostic Techniques / standards*
-
Mycobacterium tuberculosis / isolation & purification
-
Sensitivity and Specificity
-
South Africa
-
Sputum / microbiology*
-
Tuberculosis, Pulmonary / diagnosis*