Objective: To investigate the clinical therapeutic effect of biological information infrared liver therapeutic apparatus (BILT) combined with praziquantel in the treatment of patients with chronic schistosomiasis.
Methods: A case-control study was conducted. A total of 142 chronic schistosomiasis patients were divided into an experimental group (BILT combined with praziquantel) with 64 cases and a control group (routine treatment with praziquantel alone) with 78 cases on the basis of the age, gender, disease duration and liver function as paired condition. Fatigue, diarrhea, abdominal distension, liver function, hyaluronic acid (HA) and laminin (LN) were as observation indexes and the observation results were compared between two groups.
Results: Before the treatment, there were no significant differences between the two groups in the indexes above-mentioned (P > 0.05). After the treatment, the incidence rates of fatigue, diarrhea, abdominal distension, abnormal liver function, and the levels of HA and LN in the experimental group were significantly lower than those in the control group (P < 0.01).
Conclusions: BILT combined with praziquantel can significantly alleviate the short-term clinical symptoms, restore liver function and also alleviate hepatic fibrosis of the patients with chronic schistosomiasis.
[摘要]目的 了解生物信息红外肝病治疗仪 (BILT) 与吡喹酮联用对血吸虫病治疗和护理的临床效果。 方法 采用病 例对照研究, 以年龄、性别、病程、肝功能等作为配对条件, 将142 例血吸虫病患者分为BILT与吡喹酮治疗方案联用 (实验 组) 64 例和吡喹酮常规治疗方案单用 (对照组) 78 例。以乏力、腹泻、上腹饱胀、肝功能、HA 和 LN 作为观察指标, 并在两 组间比较分析。 结果 与对照组比, 实验组的治后乏力、腹泻、上腹饱胀的发生率, 以及肝功能异常率、HA 与LN水平都 显著降低 (P均< 0.01)。 结论 BILT与吡喹酮联合治疗血吸虫病患者, 能减轻患者近期临床症状, 对恢复肝功能和改善 肝纤维化有一定效果。.
Keywords: Clinical effect; Liver disease therapeutic apparatus; Praziquantel; Schistosomiasis.