[Clinical analysis of 17 cases of paragonimiasis]

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2016 Feb 26;28(2):217-219. doi: 10.16250/j.32.1374.2015223.
[Article in Chinese]

Abstract

Objective: To investigate the clinical features, diagnosis and treatment of paragonimiasis, so as to improve the prevention and treatment of it.

Methods: The clinical data of paragonimiasis patients were collected and retrospectively analyzed.

Results: Totally 17 patients were diagnosed as paragonimiasis and the main clinical features of 11 patients were cough, chest pain and fever, and the pleural effusion was found in 13 cases. Peripheral blood eosinophil percentages of all patients were significantly increased, and the detections of antibody IgG againstParagonimus parasite of ELISA method were positive in all patients. All the patients were cured after praziquantel treatment and no recurrence found in the follow-up visit.

Conclusions: The clinical features of paragonimiasis patients are diverse, and pleural effusion is quite common in imaging examinations. The eosinophil percentages and antibody detections have important values for the diagnosis of paragonimiasis. Praziquantel is an effective medicine in the treatment.

摘要目的 探讨并殖吸虫病的临床表现、诊断及治疗, 提高并殖吸虫病防治水平。方法 收集并殖吸虫病患者的 临床资料进行回顾性分析。结果 共确诊并殖吸虫病患者17例, 其中11例患者以咳嗽、胸痛、发热为主要临床表现, 13 例患者存在胸腔积液。17例患者的末梢血嗜酸性粒细胞比例29.9%~59.3%, 并殖吸虫抗体IgG (ELISA) 均为阳性。经 吡喹酮治疗后, 所有患者均治愈, 随访1~2年无复发。结论 并殖吸虫病患者临床表现形式多样化, 影像表现则以胸腔 积液多见。末梢血中嗜酸性粒细胞增多及并殖吸虫抗体检查有助于此病诊断, 吡喹酮治疗效果确切。.

Keywords: Clinical symptom; Diagnosis; Paragonimiasis; Sign; Treatment.

MeSH terms

  • Adolescent
  • Adult
  • Animals
  • Anthelmintics / administration & dosage
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Middle Aged
  • Paragonimiasis / diagnosis
  • Paragonimiasis / drug therapy*
  • Paragonimiasis / parasitology
  • Paragonimus / drug effects
  • Paragonimus / isolation & purification
  • Paragonimus / physiology
  • Pleural Effusion / diagnosis
  • Pleural Effusion / drug therapy
  • Pleural Effusion / parasitology
  • Praziquantel / administration & dosage
  • Retrospective Studies
  • Young Adult

Substances

  • Anthelmintics
  • Praziquantel