[Analyais of Toxoplasma gondii infection and related factors among special population in Changzhou City, Jiangsu Province]

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2016 Nov 18;28(6):669-673. doi: 10.16250/j.32.1374.2016172.
[Article in Chinese]

Abstract

Objective: To understand the prevalence of Toxoplasma gondii infection and related factors among special population in Changzhou City, so as to provide the evidence for formulating toxoplasmosis prevention measures.

Methods: The venous blood was collected from participants in Changzhou City for detecting IgG and IgM antibodies against T. gondii by ELISA; and an epidemiological questionnaire investigation was also conducted.

Results: Among the total 400 respondents detected, the prevalence of T. gondii infection was 15.0% and the positive rates of IgG and IgM were 15.0% and 0.8%, respectively. The T. gondii infection rates of pregnant women, HIV/AIDS patients, patients with neoplasia, and livestock and poultry breeding and processing workers were 11.0%, 11.0%, 24.0% and 14.0%, respectively. As the age increased, the infection rate of T. gondii showed an upward trend, with the highest infection rate (21.6%) among the group of respondents aged above 50 years. The infection rates of groups with different education levels were statistically different (χ2 = 11.443, P < 0.05), and there was a trend that the infection rate decreased with the increase of education level. The prevalence of T. gondii infection in pregnant women was not significantly associated with the number of pregnancies and gestational age. The infection rate of T. gondii in the live-stock and poultry breeding and processing workers increased with the length of their working years.

Conclusions: The prevalence of T. gondii infection among the special population in Changzhou City is high. Therefore, it is necessary to enhance the health education on the knowledge and information of prevention and control of toxoplasmosis, and to improve the awareness of personal protection, the hygiene practices and diet habits. In addition, more attention should be paid to T. gondii monitoring in the special population.

[摘要]目的 了解常州市特殊人群弓形虫感染状况, 探讨主要影响因素, 为科学制定弓形虫病防治措施提供依据。 方法 采集常州市调查对象静脉血, 用酶联免疫吸附法 (ELISA) 检测弓形虫IgG、IgM抗体, 并进行流行病学问卷调查。 结果 共调查检测400人, 弓形虫感染率为15.0%, 其中, IgG抗体阳性率15.0%, IgM抗体阳性率0.8%。孕妇、艾滋病病 毒感染者、肿瘤病人及畜禽产品养殖加工人员的感染率分别为11.0%、11.0%、24.0%和14.0%。感染率随着年龄增长呈上 升趋势, 尤以50岁以上组感染率最高 (21.6%)。不同文化程度人群感染率差异有统计学意义 (χ2 =11.443, P < 0.05), 且 感染率随文化程度增高而降低。孕妇弓形虫感染与怀孕次数及孕期无明显关联; 畜禽产品养殖加工人员的感染率, 随着 工龄增加呈上升趋势。 结论 常州市特殊人群的弓形虫感染率较高, 需加强弓形虫病防治知识的宣传教育, 提高个人防 护意识, 养成良好的饮食和卫生习惯, 重视特殊人群的弓形虫感染监测。.

Keywords: Changzhou City; Infection; Influential factor; Special population; Toxoplasma gondii.

MeSH terms

  • Animal Husbandry
  • Animals
  • Antibodies, Protozoan / blood
  • China
  • Cities
  • Female
  • HIV Infections / parasitology
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin M / blood
  • Livestock
  • Neoplasms / parasitology
  • Pregnancy
  • Pregnancy Complications, Parasitic / epidemiology
  • Risk Factors
  • Seroepidemiologic Studies
  • Toxoplasma
  • Toxoplasmosis / epidemiology*

Substances

  • Antibodies, Protozoan
  • Immunoglobulin G
  • Immunoglobulin M