Confirmation for conformational selection

Elife. 2018 Feb 20:7:e34923. doi: 10.7554/eLife.34923.

Abstract

NMR studies settle part of a long-standing debate about the mechanism used by the Hsp70 chaperone to recognize substrates.

Keywords: E. coli; Hsp70; biophysics; conformational selection; induced fit; methyl-TROSY NMR; molecular chaperones; structural biology.

Publication types

  • Comment

MeSH terms

  • HSP70 Heat-Shock Proteins*
  • Models, Molecular
  • Molecular Chaperones*
  • Protein Binding
  • Protein Conformation

Substances

  • HSP70 Heat-Shock Proteins
  • Molecular Chaperones