Glaucoma after chemical burns and radiation

Rom J Ophthalmol. 2016 Oct-Dec;60(4):209-215.

Abstract

Glaucoma after chemical burns represents a posttraumatic glaucoma, usually open-angle glaucoma. It is a frequent complication of chemical burns, especially with alkali and it can appear in the acute stage or as a late complication. Because of the complications and scars, the treatment is very difficult. Topical treatment is based on AC inhibitors, β-blockers, α2-agonists. Trabeculectomy, shunts, cyclophotocoagulation, and cryotherapy are the solutions in the late stages. Glaucoma after irradiation is a closing-angle secondary glaucoma. The risk factors such as the radiation dose and the volume of the radiated structure are important in the appearance and evolution of this type of glaucoma. Topical treatment is usually ineffective, the preferable options being laser and surgical treatments. Although it is not a frequently seen pathology, it is important to know how to diagnose and treat this type of glaucoma. There are various options available for treatment, but choosing one is difficult because of the possible complications.

Keywords: IOP; alkali; chemical burn; radiation; secondary glaucoma.

Publication types

  • Review

MeSH terms

  • Antihypertensive Agents / therapeutic use
  • Burns, Chemical / classification
  • Burns, Chemical / etiology*
  • Cryotherapy
  • Eye Burns / chemically induced*
  • Glaucoma, Open-Angle / diagnosis
  • Glaucoma, Open-Angle / etiology*
  • Glaucoma, Open-Angle / therapy
  • Humans
  • Laser Coagulation
  • Radiation Injuries / classification
  • Radiation Injuries / etiology*
  • Trabeculectomy

Substances

  • Antihypertensive Agents