Two new lignans from Horsfieldia kingii

Nat Prod Res. 2019 Jan;33(1):95-100. doi: 10.1080/14786419.2018.1437429. Epub 2018 Feb 15.

Abstract

Two new dibenzylbutyrolactol lignans and three known dibenzylbutyrolactone lignans were isolated from the twigs and leaves of Horsfieldia kingii. Their structures were elucidated by spectroscopic analysis. Cytotoxicity evaluation of these compounds against five human tumour lines showed no inhibitory effects.

Keywords: Horsfielenide; lignans.

MeSH terms

  • Cell Line, Tumor
  • Drug Screening Assays, Antitumor
  • Humans
  • Lignans / chemistry
  • Lignans / isolation & purification*
  • Lignans / toxicity
  • Molecular Structure
  • Myristicaceae / chemistry*
  • Plant Extracts / chemistry*
  • Plant Leaves / chemistry
  • Spectrum Analysis

Substances

  • Lignans
  • Plant Extracts