Epibulbar complex cartilaginous choristoma: A distinctive clinicopathological case series and literature review

Medicine (Baltimore). 2018 Feb;97(7):e9902. doi: 10.1097/MD.0000000000009902.

Abstract

To newly describe the clinical and histopathological characteristics of epibulbar complex cartilaginous choristoma incidentally observed in a series of pterygium excision patients.Noncomparative case series with chart review of 8 patients.During a 4-year period, we identified 8 cases of conventional unilateral nasal subpterygial cartilaginous choristoma in 1799 pterygium patients and analyzed their clinicopathological features. The incidence rate of this entity is 0.44% in pterygium patients. All of the cartilaginous choristomas were buried deep in the caruncle, covered by the pterygium, and embedded in tenon facia tissue. Its clinicopathological characteristics include hyaline cartilaginous tissue that is surrounded by fibrous connective tissue and smooth muscle bundles. S-100 protein-staining specifically revealed chondrocytes embedded within chondroid matrix.Epibulbar complex cartilaginous choristoma covered by pterygia and predominantly observed in the older population is rare. The lesions were buried deep in the caruncle, covered by the pterygium and embedded in tenon fascia tissue. These findings are inconsistent with those in previous reports.

Publication types

  • Observational Study

MeSH terms

  • Age Factors
  • China / epidemiology
  • Choristoma* / epidemiology
  • Choristoma* / pathology
  • Choristoma* / surgery
  • Conjunctiva*
  • Female
  • Humans
  • Hyaline Cartilage / pathology
  • Incidental Findings
  • Male
  • Middle Aged
  • Ophthalmologic Surgical Procedures* / methods
  • Ophthalmologic Surgical Procedures* / statistics & numerical data
  • Pterygium* / epidemiology
  • Pterygium* / pathology
  • Pterygium* / surgery
  • Risk Factors
  • S100 Proteins / analysis

Substances

  • S100 Proteins