Novel complication of an emerging disease: Invasive Klebsiella pneumoniae liver abscess syndrome as a cause of acute respiratory distress syndrome

Anupam Gupta; Saad Bhatti; Anatoly Leytin; Oleg Epelbaum

doi:10.4081/cp.2018.1021

Novel complication of an emerging disease: Invasive Klebsiella pneumoniae liver abscess syndrome as a cause of acute respiratory distress syndrome

Clin Pract. 2017 Jul 18;8(1):1021. doi: 10.4081/cp.2018.1021. eCollection 2018 Jan 8.

Authors

Anupam Gupta¹, Saad Bhatti², Anatoly Leytin³, Oleg Epelbaum⁴

Affiliations

¹ Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Elmhurst Hospital Center, Icahn School of Medicine at Mount Sinai, Elmhurst, NY.
² Division of Surgical Critical Care, Department of Surgery, Elmhurst Hospital Center, Icahn School of Medicine at Mount Sinai, Elmhurst, NY.
³ Department of Pathology Elmhurst Hospital Center, Icahn School of Medicine at Mount Sinai, Elmhurst, NY.
⁴ Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Internal Medicine, Westchester Medical Center, New York Medical College, Valhalla, NY, USA.

Abstract

Klebsiella pneumoniae is an increasingly recognized cause of a unique invasive syndrome manifesting as pyogenic liver abscess and hematogenous extrahepatic dissemination to a variety of sites, including the lung. Originally described only in Asia, this entity has now been reported across continents and ethnicities. Intrathoracic complications of invasive Klebsiella pneumoniae liver abscess syndrome (IKPLAS) have been characterized sporadically but have not been the subject of an all-encompassing investigation. Review of the English-language literature yields no reports of the acute respiratory distress syndrome as a consequence of IKPLAS. Herein we report what, to our knowledge, is the first such description.

Keywords: ARDS; Klebsiella pneumoniae; liver abscess.