Advances in Heparins and Related Research. An Epilogue

Molecules. 2018 Feb 12;23(2):390. doi: 10.3390/molecules23020390.

Abstract

The discovery of heparin in 1916 by Jay McLean, a medical student at Johns Hopkins University, not only provided a universal anticoagulant, but also laid the foundation for the discipline of hemostasis and thrombosis[...].

Publication types

  • Editorial
  • Historical Article

MeSH terms

  • Animals
  • Biomedical Research / history*
  • Blood Coagulation / physiology
  • Cattle
  • Heparin / analogs & derivatives
  • Heparin / biosynthesis
  • Heparin / history
  • Heparin / therapeutic use*
  • Heparin Antagonists / therapeutic use
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Practice Guidelines as Topic
  • Protamines / therapeutic use
  • Quality Control
  • Sheep
  • Swine
  • Thrombosis / blood
  • Thrombosis / drug therapy*
  • Thrombosis / history
  • Thrombosis / physiopathology

Substances

  • Heparin Antagonists
  • Protamines
  • Heparin