Norditerpenoid alkaloids from Aconitum manshuricum

Katsuhiro Ishimi; Mitsuko Makino; Yasuo Asada; Yoshiyuki Ichinohe; Yasuo Fujimoto

doi:10.1007/s11418-006-0044-4

Norditerpenoid alkaloids from Aconitum manshuricum

J Nat Med. 2006 Jul;60(3):255-257. doi: 10.1007/s11418-006-0044-4. Epub 2006 Apr 14.

Authors

Katsuhiro Ishimi¹, Mitsuko Makino², Yasuo Asada³, Yoshiyuki Ichinohe³, Yasuo Fujimoto²

Affiliations

¹ College of Science and Technology, Nihon University, 7-24-1 Narashinodai, Funabashi, Chiba 274-8501, Japan. ishimi@chem.ge.cst.nihon-u.ac.jp.
² College of Humanities and Sciences, Nihon University, 3-25-40 Sakurajosui, Setagaya, Tokyo 156-8550, Japan.
³ College of Science and Technology, Nihon University, 7-24-1 Narashinodai, Funabashi, Chiba 274-8501, Japan.

PMID: 29435883
DOI: 10.1007/s11418-006-0044-4

Abstract

A new norditerpenoid alkaloid, manshuritine (1) has been isolated from Aconitum manshuricum, together with seven known alkaloids; beiwudine (2), beiwutine (3), 16-epi-pyromesaconitine (4), mesaconitine (5), aconitine (6), hypaconitine (7) and 14-benzoylmesaconine (8). The structure of the new compound was elucidated on the basis of spectral data and chemical correlations.

Keywords: Aconitum manshuricum; Manshuritine; Norditerpenoid alkaloids; Ranunculaceae.