Synthesis of a single 1,8-naphthalimide fluorophore as a molecular logic lab for simultaneously detecting of Fe3+, Hg2+ and Cu2

Awad I Said; Nikolai I Georgiev; Vladimir B Bojinov

doi:10.1016/j.saa.2018.02.005

Synthesis of a single 1,8-naphthalimide fluorophore as a molecular logic lab for simultaneously detecting of Fe³⁺, Hg²⁺ and Cu²

Spectrochim Acta A Mol Biomol Spectrosc. 2018 May 5:196:76-82. doi: 10.1016/j.saa.2018.02.005. Epub 2018 Feb 5.

Authors

Awad I Said¹, Nikolai I Georgiev², Vladimir B Bojinov³

Affiliations

¹ Department of Chemistry, Faculty of Science, Assiut University, Assiut, Egypt.
² Department of Organic Synthesis, University of Chemical Technology and Metallurgy, 8 Kliment Ohridsky Str., 1756 Sofia, Bulgaria.
³ Department of Organic Synthesis, University of Chemical Technology and Metallurgy, 8 Kliment Ohridsky Str., 1756 Sofia, Bulgaria. Electronic address: vlbojin@uctm.edu.

PMID: 29433042
DOI: 10.1016/j.saa.2018.02.005

Abstract

A novel fluorescence sensing 1,8-naphthalimide fluorophore is synthesized and investigated. The novel probe comprising two different binding moieties is capable to detect selectively Fe³⁺ over the other representative metal ions as well as a combination of biologically important cations such as Fe³⁺, Cu²⁺ and Hg²⁺ in the physiological range without an interfering effect of the pHs. Due to the remarkable fluorescence changes in the presence of Fe³⁺, Hg²⁺ and Cu²⁺ ions, INH and AND logic gates are executed and the system is able to act as a single output combinatorial logic circuit with three chemical inputs.

Keywords: 1,8-Naphthalimide; Fluorescence probe; INH and AND logic gates; Internal charge transfer (ICT); Multiple analyte detection; Single output combinatorial logic circuit with three chemical inputs.