H-scan analysis of thyroid lesions

J Med Imaging (Bellingham). 2018 Jan;5(1):013505. doi: 10.1117/1.JMI.5.1.013505. Epub 2018 Feb 7.

Abstract

The H-scan analysis of ultrasound images is a matched-filter approach derived from analysis of scattering from incident pulses in the form of Gaussian-weighted Hermite polynomial functions. This framework is applied in a preliminary study of thyroid lesions to examine the H-scan outputs for three categories: normal thyroid, benign lesions, and cancerous lesions within a total group size of 46 patients. In addition, phantoms comprised of spherical scatterers are analyzed to establish independent reference values for comparison. The results demonstrate a small but significant difference in some measures of the H-scan channel outputs between the different groups.

Keywords: medical imaging; scattering; tissues; ultrasonics.