The bone scintigraphy in the diagnosis and management in children with febrile osteoarticular pain

Tunis Med. 2017 Feb;95(2):109-114.

Abstract

Background: Bone and joint infections are common diseases in pediatrics. They still are a public health problem in Tunisia. The diagnosis is based on clinical, biological, radiological and skeletal scintigraphy arguments. The purpose of this study is to determine the contribution of triple phase bone scan in the exploration of musculoskeletal pain febrile child.

Methods: This was a descriptive and retrospective study. It was conducted over a period of 5 years. It has interested all children explored in nuclear medicine department with suspected acute osteomyelitis (OMA) , osteoarthritis (OA) or septic arthritis (SA) referred from Orthopaedic Infantile service. All these patients had, alongside the conventional radiologic exams, a triple phase bone scan HMDP-Tc99m.

Results: We collected 62 patients. Among the selected diagnoses, there were: 22 OMA, 4 OA, 4 SA. The mean age of the patients was 5.58 years with a male predominance. The main reason for consultation was pain. Fever was ≥ 38° C in 80 % of cases. The preferential localization was the lower limb (93.5 %). The quantitative and qualitative bone scan abnormalities objectified led to a correct diagnosis of: 18 OMA, 3 OA and 2 SA with a respectively estimated sensitivity and specificity of 76.6% and 90.6% in the all population.

Conclusions: Bone scan demonstrates early abnormalities allowing osteoaricular infection diagnosis. It highlights the infection site, and draws a map of the lesions. Currently, imaging modalities differ in their availability, their cost, their input and diagnostic accuracy but they are complementary.

Publication types

  • Evaluation Study

MeSH terms

  • Acute Disease
  • Adolescent
  • Arthritis, Infectious / diagnosis
  • Arthritis, Infectious / epidemiology
  • Arthritis, Infectious / therapy
  • Child
  • Child, Preschool
  • Female
  • Fever / complications
  • Fever / diagnosis*
  • Fever / epidemiology
  • Fever / therapy*
  • Hospitalization / statistics & numerical data
  • Humans
  • Infant
  • Male
  • Osteoarthritis / complications
  • Osteoarthritis / diagnosis*
  • Osteoarthritis / epidemiology
  • Osteoarthritis / therapy*
  • Osteomyelitis / diagnosis
  • Osteomyelitis / epidemiology
  • Osteomyelitis / therapy
  • Pain / complications
  • Pain / diagnosis*
  • Pain / epidemiology
  • Pain Management / methods
  • Predictive Value of Tests
  • Radionuclide Imaging* / methods
  • Radionuclide Imaging* / standards
  • Retrospective Studies
  • Sensitivity and Specificity
  • Technetium Tc 99m Medronate / analogs & derivatives
  • Technetium Tc 99m Medronate / chemistry
  • Tomography, X-Ray Computed
  • Tunisia / epidemiology

Substances

  • technetium Tc 99m hydroxymethylene diphosphonate
  • Technetium Tc 99m Medronate