Incidence of filled antidepressant prescriptions among people with newly diagnosed diabetes and its interaction with occupational status within the working population of Denmark 1996-2010

Prim Care Diabetes. 2018 Aug;12(4):305-311. doi: 10.1016/j.pcd.2018.01.002. Epub 2018 Mar 1.

Abstract

Aims: People with diabetes have heightened levels of depressive symptoms, but less is known about the development of these symptoms in relation to diabetes duration. In this study, we examined the use of prescribed antidepressants in the first five years after diagnosis of diabetes among the working-age population in Denmark.

Methods: All Danish adults aged 18-54 years, diagnosed with diabetes in the study period were included. Diabetes status and purchase of prescription antidepressants were obtained from validated population registers. Data analysis focused on filled antidepressant prescriptions at ≤1 and ≤5years from diagnosis with diabetes.

Results: 35,677 people diagnosed with diabetes were included in the study. At ≤1 year post-diagnosis, 2.6% had filled antidepressant prescriptions. At ≤5years, this figure rose to 10.4%. Overall, both female gender and lower socioeconomic status were associated with higher incidence of filled antidepressant prescriptions. Diabetes duration modified the degree of differences between men and women and socioeconomic strata.

Conclusion: Diagnosis with diabetes immediately impacts mental wellbeing, with higher rates of filled antidepressant prescriptions in the first year after diagnosis. People of working age diagnosed with diabetes face specific challenges and addressing such challenges would enhance patient experiences. Focus on mental health in the clinical encounter with people newly diagnosed with diabetes is warranted and important.

Keywords: Antidepressants; Diabetes Mellitus; Diagnosis; Socioeconomic status.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Antidepressive Agents / therapeutic use*
  • Denmark / epidemiology
  • Depression / diagnosis
  • Depression / drug therapy*
  • Depression / epidemiology
  • Depression / psychology
  • Diabetes Mellitus / diagnosis*
  • Diabetes Mellitus / epidemiology
  • Diabetes Mellitus / psychology
  • Drug Prescriptions
  • Employment*
  • Female
  • Humans
  • Incidence
  • Job Description
  • Male
  • Mental Health
  • Middle Aged
  • Registries
  • Risk Factors
  • Sex Factors
  • Social Class
  • Social Determinants of Health
  • Time Factors
  • Young Adult

Substances

  • Antidepressive Agents