1 University Hospital Southampton, Southampton, UK San Raffaele Hospital, Milan, Italy Ghent University Hospital Medical School, Ghent, Belgium Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo, Norway Antoine-Beclere Hospital, Paris, France Groeninge Hospital, Kortrijk, Belgium University of Navarra Hospital, Pamplona, Spain Antoine-Beclere Hospital, Paris, France San Raffaele Hospital, Milan, Italy Ghent University Hospital Medical School, Ghent, Belgium Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo, Norway University Hospital Southampton, Southampton, UK.