Rare mutations in apoptosis related genes APAF1, CASP9, and CASP3 contribute to human neural tube defects

Cell Death Dis. 2018 Jan 19;9(2):43. doi: 10.1038/s41419-017-0096-2.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Apoptosis / genetics
  • Apoptotic Protease-Activating Factor 1 / genetics*
  • Asian People / genetics
  • Caspase 3 / genetics*
  • Caspase 9 / genetics*
  • HEK293 Cells
  • Humans
  • Mutation*
  • Neural Tube Defects / enzymology
  • Neural Tube Defects / genetics*
  • Neural Tube Defects / pathology

Substances

  • APAF1 protein, human
  • Apoptotic Protease-Activating Factor 1
  • CASP3 protein, human
  • CASP9 protein, human
  • Caspase 3
  • Caspase 9