Chronic strongyloidiasis with recurrent asthma exacerbations and steroid-associated 'hives'

BMJ Case Rep. 2018 Jan 17:2018:bcr2017221877. doi: 10.1136/bcr-2017-221877.

Abstract

A 74-year-old man experienced worsening asthma for several years. Oral steroids were required on multiple occasions for asthma treatment. During his steroid courses, he developed a hive-like rash, which would resolve after completion of each steroid course. He was from Romania, and had lived in the USA for many years. Laboratory testing had shown eosinophilia. He was eventually diagnosed with strongyloidiasis by serology. Treatment with ivermectin led to marked improvement but not resolution of his long-term asthma. His hive-like rash, which was likely larva currens, did not recur with a subsequent steroid course. Improved recognition of strongyloidiasis, particularly in steroid-treated patients, is needed.

Keywords: travel medicine; tropical medicine (infectious disease).

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Animals
  • Antiparasitic Agents / therapeutic use
  • Asthma / drug therapy
  • Asthma / parasitology*
  • Chronic Disease
  • Disease Progression
  • Eosinophilia / drug therapy
  • Eosinophilia / parasitology*
  • Humans
  • Ivermectin / therapeutic use
  • Male
  • Recurrence
  • Steroids / adverse effects*
  • Strongyloides stercoralis
  • Strongyloidiasis / complications*
  • Strongyloidiasis / drug therapy
  • Strongyloidiasis / parasitology
  • Urticaria / chemically induced
  • Urticaria / parasitology*

Substances

  • Antiparasitic Agents
  • Steroids
  • Ivermectin