Twisted Charge-Transfer Antennae for Ultra-Bright Terbium(III) and Dysprosium(III) Bioprobes

Anh Thy Bui; Amandine Roux; Alexei Grichine; Alain Duperray; Chantal Andraud; Olivier Maury

doi:10.1002/chem.201705933

Twisted Charge-Transfer Antennae for Ultra-Bright Terbium(III) and Dysprosium(III) Bioprobes

Chemistry. 2018 Mar 7;24(14):3408-3412. doi: 10.1002/chem.201705933. Epub 2018 Feb 5.

Authors

Anh Thy Bui¹, Amandine Roux¹, Alexei Grichine², Alain Duperray², Chantal Andraud¹, Olivier Maury¹

Affiliations

¹ Univ Lyon, ENS de Lyon, CNRS UMR 5182, Université Claude Bernard Lyon 1, Laboratoire de Chimie, 69342, Lyon, France.
² Institute for Advanced Biosciences, Inserm U1209, CNRS UMR5309, Université. Grenoble Alpes, 38000, Grenoble, France.

PMID: 29341302
DOI: 10.1002/chem.201705933

Abstract

The design of original twisted charge transfer antennae in which a non-planar geometry is enforced thanks to one or two bulky ortho-Me substituents allows us to prepare the corresponding ultra-bright Tb^III and Dy^III bioprobes. The brightness of the Tb^III derivative compares well with that of the benchmark Tb-Lumi4 complex. The first bio-imaging experiments with a Dy^III luminescent bioprobe are also reported.

Keywords: bioimaging; dysprosium; lanthanides; luminescence; terbium.