The complement system in the airway epithelium: An overlooked host defense mechanism and therapeutic target?

Hrishikesh S Kulkarni; M Kathryn Liszewski; Steven L Brody; John P Atkinson

doi:10.1016/j.jaci.2017.11.046

The complement system in the airway epithelium: An overlooked host defense mechanism and therapeutic target?

J Allergy Clin Immunol. 2018 May;141(5):1582-1586.e1. doi: 10.1016/j.jaci.2017.11.046. Epub 2018 Jan 12.

Authors

Hrishikesh S Kulkarni¹, M Kathryn Liszewski², Steven L Brody³, John P Atkinson⁴

Affiliations

¹ Division of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University in St Louis, St Louis, Mo; Division of Rheumatology, Department of Medicine, Washington University in St Louis, St Louis, Mo.
² Division of Rheumatology, Department of Medicine, Washington University in St Louis, St Louis, Mo.
³ Division of Pulmonary and Critical Care Medicine, Department of Medicine, Washington University in St Louis, St Louis, Mo.
⁴ Division of Rheumatology, Department of Medicine, Washington University in St Louis, St Louis, Mo. Electronic address: j.p.atkinson@wustl.edu.

No abstract available

Keywords: Complement; allergic rhinitis; anaphylatoxins; asthma; bronchiolitis; cystic fibrosis; epithelial cells; ovalbumin; properdin; pulmonary fibrosis.

Publication types

Editorial
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Asthma / immunology
Complement System Proteins / immunology*
Humans
Respiratory Mucosa / immunology*
Respiratory System / immunology*

Substances

Complement System Proteins

Publication types

MeSH terms

Substances

Grants and funding