Assessment of oral cancer pain, anxiety, and quality of life of oral squamous cell carcinoma patients with invasive treatment procedure

Oral Maxillofac Surg. 2018 Mar;22(1):83-90. doi: 10.1007/s10006-018-0672-3. Epub 2018 Jan 13.

Abstract

Purpose: Depending on its stage on diagnosis, oral squamous cell carcinoma (OSCC) might cause excruciating pain and decreased quality of life. As for treatment, the treatment of OSCC might vary from chemotherapy to surgery. The objective of the current study was to assess the preoperative and postoperative oral cancer pain, anxiety, and quality of life of OSCC patients with invasive treatment procedure.

Methods: The current study was conducted by interviewing 21 (10 males; 11 females) patients who had been diagnosed with stage 3 and stage 4 OSCC and about to go through surgery at the inpatient ward of Surgical Oncology Department, Hasan Sadikin Hospital, Bandung, Indonesia. A preoperative and interview was conducted by using the Hospital Anxiety and Depression Scale (HADS), the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QOL)-C30, the shortened EORTC QOL Questionnaire for Oesophageal Cancer (OES)18, the visual analog scale (VAS), and the University of California San Francisco (UCSF) Oral Cancer Pain Questionnaire. All data were analyzed to evaluate the preoperative and postoperative effect.

Results: The current study showed a significant decrease of the postoperative oral pain (p < 0.01) and anxiety level (p < 0.01), while postoperative patient' quality of life was significantly (p < 0.01) increased.

Conclusion: Despite of the invasive procedure that might cause postoperative effect, OSCC patients in the current study showed a better quality of life after cancer removal.

Keywords: Anxiety; Oral cancer; Oral cancer pain; Oral squamous cell carcinoma; Quality of life.

MeSH terms

  • Adult
  • Aged
  • Anxiety / psychology*
  • Cancer Pain / psychology*
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / psychology
  • Carcinoma, Squamous Cell / surgery*
  • Female
  • Humans
  • Indonesia
  • Male
  • Middle Aged
  • Mouth Neoplasms / pathology
  • Mouth Neoplasms / psychology
  • Mouth Neoplasms / surgery*
  • Neoplasm Staging
  • Pain Measurement*
  • Pain, Postoperative / psychology
  • Quality of Life / psychology*
  • Young Adult