Meningeal marginal zone B-cell lymphoma: The meningioma trap

Eur Ann Otorhinolaryngol Head Neck Dis. 2018 Apr;135(2):131-132. doi: 10.1016/j.anorl.2017.12.002. Epub 2018 Jan 10.

Abstract

Objective: To report a case of marginal zone MALT lymphoma of the temporal dura mater, initially mistaken for temporal meningioma.

Case report: A 60-year-old immunocompetent woman, followed for more than 10 years for temporal meningioma causing vertigo and mixed hearing loss, presented with cervical lymphadenopathy, revealing marked progression of an intracranial lesion, leading to a diagnosis of marginal zone MALT lymphoma based on histological examination of a cervical lymph node. Treatment with 6 cycles of rituximab and bendamustine allowed complete remission of cervical lymph node and intracranial lesions, confirming the diagnosis of temporal dural mater lymphoma.

Conclusion: Primary dural lymphoma must be part of the differential diagnosis of meningioma. Long-term follow-up allows correction of the diagnosis.

Keywords: Cervical adenopathy; En-plaque meningioma; Hearing loss; Intraosseous meningioma; Primary dural lymphoma; Temporal meningioma.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents, Alkylating / therapeutic use
  • Antineoplastic Agents, Immunological / therapeutic use
  • Bendamustine Hydrochloride / therapeutic use
  • Diagnosis, Differential
  • Dura Mater / pathology*
  • Female
  • Humans
  • Lymphoma, B-Cell, Marginal Zone / diagnosis*
  • Lymphoma, B-Cell, Marginal Zone / drug therapy
  • Meningeal Neoplasms / diagnosis*
  • Meningioma / diagnosis*
  • Middle Aged
  • Rituximab / therapeutic use
  • Treatment Outcome

Substances

  • Antineoplastic Agents, Alkylating
  • Antineoplastic Agents, Immunological
  • Rituximab
  • Bendamustine Hydrochloride