Immune Training Unlocks Innate Potential

Wilbur M Song; Marco Colonna

doi:10.1016/j.cell.2017.12.034

Immune Training Unlocks Innate Potential

Cell. 2018 Jan 11;172(1-2):3-5. doi: 10.1016/j.cell.2017.12.034.

Authors

Wilbur M Song¹, Marco Colonna²

Affiliations

¹ Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA.
² Department of Pathology and Immunology, Washington University School of Medicine, Saint Louis, MO, USA. Electronic address: mcolonna@wustl.edu.

PMID: 29328917
DOI: 10.1016/j.cell.2017.12.034

Abstract

Trained immunity is a form of innate immune memory with distinct features from classical adaptive immune memory. In the current issues of Cell and Cell Host & Microbe, five studies from the International Trained Immunity Consortium shed light on mechanisms and functional consequences of this phenomenon on cellular and whole-organism levels.

Publication types

Comment

MeSH terms

Adaptive Immunity*
Humans
Immune System Diseases
Immunity, Innate*
Immunologic Memory
Mevalonic Acid

Substances

Mevalonic Acid