Background: Early recognition of sepsis is challenging, especially in the surgical patient. Because of the non-specific nature of the initial signs and symptoms, delays in recognition are all too common. To improve the early identification of sepsis, screening tools have been developed, and several papers have described their results. This article reviews the available sepsis screening tools.
Methods: A PubMed search was performed using the search terms "sepsis" and "shock," "electronic alert," "clinical decision support," and "early warning systems." The papers found were reviewed to determine their relevance to the topic of sepsis screening, and outcome data were extracted from appropriate papers.
Results: Multiple sepsis screening tools were identified with differing performance characteristics. These tools are reviewed individually along with a summary of their sensitivity, specificity, and positive and negative predictive values.
Conclusions: Clearly, sepsis screening has the potential to improve patient outcomes by aiding clinicians in the early recognition of the condition, enabling early implementation of evidence-based therapies. However, significant challenges remain, including identifying an optimal screening tool. Continued research is needed into the development and integration of automated screening tools that will be effective in a variety of clinical settings.
Keywords: infection; screening test; sepsis; septic shock.