High-dose biotin in infants mimics biochemical hyperthyroidism with some commercial assays

Clin Endocrinol (Oxf). 2018 Mar;88(3):507-510. doi: 10.1111/cen.13547. Epub 2018 Jan 26.

Authors

Ved Bhushan Arya¹, Michal Ajzensztejn¹, Gayle Appleby¹, Sue Oddy², David Halsall², Krishna Chatterjee³, Carla Moran³, Tony Hulse¹

Affiliations

¹ Department of Paediatric Endocrinology and Diabetes, Evelina London Children Hospital, Guy's and St Thomas' NHS Foundation Trust, London, UK.
² Department of Clinical Biochemistry, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
³ MRC Institute of Metabolic Science, Wellcome Trust, University of Cambridge, Cambridge, UK.

PMID: 29314108
DOI: 10.1111/cen.13547

No abstract available

Publication types

Letter

MeSH terms

Biotin / analysis*
Diagnosis, Differential
Humans
Hyperthyroidism / diagnosis*
Infant
Infant, Newborn
Reagent Kits, Diagnostic / standards
Thyroid Function Tests / standards*

Substances

Reagent Kits, Diagnostic
Biotin