Extracellular fungal polyol lipids: A new class of potential high value lipids

Luis A Garay; Irnayuli R Sitepu; Tomas Cajka; Jian Xu; Hui Ean Teh; J Bruce German; Zhongli Pan; Stephanie R Dungan; David E Block; Kyria L Boundy-Mills

doi:10.1016/j.biotechadv.2018.01.003

Extracellular fungal polyol lipids: A new class of potential high value lipids

Biotechnol Adv. 2018 Mar-Apr;36(2):397-414. doi: 10.1016/j.biotechadv.2018.01.003. Epub 2018 Jan 5.

Authors

Affiliations

¹ Phaff Yeast Culture Collection, Department of Food Science and Technology, University of California, One Shields Ave, Davis, CA 95616, USA. Electronic address: lgaray@ucdavis.edu.
² Phaff Yeast Culture Collection, Department of Food Science and Technology, University of California, One Shields Ave, Davis, CA 95616, USA; Biotechnology Department, Indonesia International Institute for Life Sciences (i3L), Jalan Pulo Mas Barat Kav. 88, East Jakarta, DKI Jakarta 13210, Indonesia. Electronic address: irsitepu@ucdavis.edu.
³ UC Davis Genome Center-Metabolomics, University of California Davis, 451 Health Sciences Drive, Davis, CA 95616, USA. Electronic address: tcajka@ucdavis.edu.
⁴ Department of Food Science and Technology, University of California Davis, One Shields Ave, Davis, CA 95616, USA. Electronic address: kevxu@ucdavis.edu.
⁵ Department of Biological and Agricultural Engineering, University of California Davis, One Shields Ave, Davis, CA 95616, USA. Electronic address: hteh@ucdavis.edu.
⁶ Department of Food Science and Technology, University of California Davis, One Shields Ave, Davis, CA 95616, USA.
⁷ Department of Biological and Agricultural Engineering, University of California Davis, One Shields Ave, Davis, CA 95616, USA; Healthy Processed Foods Research Unit, Western Regional Research Center, USDA, Agricultural Research Service, 800 Buchanan Street, Albany, CA 94710, USA. Electronic address: zlpan@ucdavis.edu.
⁸ Department of Food Science and Technology, University of California Davis, One Shields Ave, Davis, CA 95616, USA; Department of Chemical Engineering, University of California Davis, One Shields Ave, Davis, CA 95616, USA. Electronic address: srdungan@ucdavis.edu.
⁹ Department of Viticulture and Enology, University of California Davis, One Shields Avenue, Davis, CA 95616, USA; Chemical Engineering and Material Science, University of California Davis, One Shields Avenue, Davis, CA 95616, USA. Electronic address: deblock@ucdavis.edu.
¹⁰ Phaff Yeast Culture Collection, Department of Food Science and Technology, University of California, One Shields Ave, Davis, CA 95616, USA. Electronic address: klbmills@ucdavis.edu.

PMID: 29309812
DOI: 10.1016/j.biotechadv.2018.01.003

Abstract

Extracellular fungal glycolipid biosurfactants have attracted attention because productivities can be high, cheap substrates can be used, the molecules are secreted into the medium and the downstream processing is relatively simple. Three classes of extracellular fungal glycolipid biosurfactants have provided most of the scientific advances in this area, namely sophorolipids, mannosylerythritol lipids and cellobioselipids. Polyol lipids, a fourth class of extracellular fungal glycolipid biosurfactants, comprise two groups of molecules: liamocins produced by the yeast-like fungus Aureobasidium pullulans, and polyol esters of fatty acids, produced by some Rhodotorula yeast species. Both are amphiphilic, surface active molecules with potential for commercial development as surfactants for industrial and household applications. The current knowledge of polyol lipids highlights an emerging group of extracellular fungal glycolipid biosurfactants and provides a perspective of what next steps are needed to harness the benefits and applications of this novel group of molecules.

Keywords: Aureobasidium; Biorefinery; Extracellular fungal glycolipid biosurfactants; Liamocins; Polyol esters of fatty acids; Rhodotorula.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

MeSH terms

Bioreactors
Extracellular Space* / chemistry
Extracellular Space* / metabolism
Fungi* / chemistry
Fungi* / metabolism
Lipids*
Polymers*
Surface-Active Agents

Substances

Lipids
Polymers
Surface-Active Agents
polyol

Grants and funding

S10 RR031630/RR/NCRR NIH HHS/United States