Inert gas rebreathing - helpful tool in the management of left ventricular assist device patients

Perfusion. 2018 Jul;33(5):335-338. doi: 10.1177/0267659117751621. Epub 2018 Jan 4.

Abstract

In patients with left ventricular assist devices (LVAD), exercise capacity is a decisive factor regarding the quality of life. When evaluating exercise capacity, precise information about the total cardiac output generated is crucial. To date, complex measurements using a right-heart catheter were necessary in order to determine total cardiac output. The inert gas rebreathing method facilitates non-invasive, direct and valid measurement of total cardiac output as well as associated parameters, like the difference in arteriovenous oxygen saturation, both at rest and during exercise. It is the aim of this paper to focus on this conclusive method which is, despite its simplicity and low-risk reproducibility, rarely used within the framework of LVAD patient treatment at the present time. The test protocol used at our hospital is presented to facilitate the implementation of this helpful tool in other interested institutions.

Keywords: exercise capacity; inert gas rebreathing; left ventricular assist device.

MeSH terms

  • Administration, Inhalation
  • Adult
  • Cardiac Output*
  • Exercise Test / methods*
  • Heart-Assist Devices*
  • Hemodynamics
  • Humans
  • Male
  • Middle Aged
  • Nitrous Oxide / administration & dosage*
  • Oxygen Consumption
  • Quality of Life
  • Respiration
  • Sulfur Hexafluoride / administration & dosage*
  • Ventricular Function, Left*

Substances

  • Nitrous Oxide
  • Sulfur Hexafluoride