Short-term fluctuation of lens corneal distance and clinical correlation with phacodonesis

Graefes Arch Clin Exp Ophthalmol. 2018 Mar;256(3):567-573. doi: 10.1007/s00417-017-3862-z. Epub 2017 Dec 26.

Abstract

Background: To analyze the role of short-term lens-corneal distance (LCD) fluctuation in quantifying preoperative phacodonesis and predicting intraoperative zonular weakness.

Methods: Patients were divided into control (lens without clinical phacodonesis) and study (lens with suspicious and clinical phacodonesis) groups for evaluation. Slit-lamp examination followed by IOLMaster (Carl Zeiss) for LCD assessment was performed. Five readings were taken at five time points (0 s, 15 s, 30 s, 45 s & 60 s) continuously over a minute (short term) for the LCD fluctuation calculation.

Results: A total of 135 eyes (82 controls and 53 study) were assessed. Study group included 32 (60.3%) suspicious and 21 (39.6%) moderate to severe phacodonesis. There was difference between the control and study eyes (p = 0.000) in short-term LCD fluctuation. Twenty-one study eyes (39.6%) showed LCD difference > 1 mm, including 11 eyes (52.3%) with > 2 mm. There was a difference in LCD with respect to severity of phacodonesis (p = 0.000). In the study eyes, 13 eyes underwent glued IOL implantation (clinical phacodonesis - ten, suspicious phacodonesis - three), and two eyes (suspicious phacodonesis) had glued capsular hook. Thirteen eyes (clinical phacodonesis - ten, suspicious phacodonesis - three) required intraoperative vitrectomy due to vitreous ingress. Intraoperative zonular weakness in 62.5% of eyes with suspicious donesis and association (Chi-square = 0.000) of weakness with preoperative LCD fluctuation was noted.

Conclusions: Short-term lens-corneal distance fluctuation can be used as a parameter for quantifying lens stability and as an aid in assessing the intraoperative risk.

Keywords: Lens movement; Lens stability; Lens–corneal distance (LCD); Phacodonesis; Short-term fluctuation in LCD.

Publication types

  • Comparative Study
  • Observational Study

MeSH terms

  • Cataract / diagnosis*
  • Cornea / diagnostic imaging*
  • Female
  • Follow-Up Studies
  • Humans
  • Lens, Crystalline / diagnostic imaging*
  • Male
  • Middle Aged
  • Prospective Studies
  • Slit Lamp Microscopy
  • Visual Acuity*