Chromosomal DNA replication starts at a specific region called an origin of replication. Until recently, all organisms were thought to require origins to replicate their chromosomes. It was recently discovered that some archaeal species do not utilize origins of replication under laboratory growth conditions.
Keywords: DNA replication; archaea; genetics; initiation of DNA replication; origin of replication; recombination-dependent DNA replication.
Published by Elsevier Ltd.