The effect of age and compression strength on venous leg ulcer healing

Phlebology. 2018 Oct;33(9):618-626. doi: 10.1177/0268355517749112. Epub 2017 Dec 20.

Abstract

Objectives The aim of the study is to compare proportions of venous leg ulcers healed in patients treated with two different sub-bandage pressure values in relation to age. Methods The study included 102 outpatients with venous leg ulcers, one group with moderate compression pressure of 35-40 mmHg and the second with high pressure >45 mmHg. Each group was divided into two subgroups according to the age (≥65 vs. <65 years). Computerized planimetry was used to measure the size of the ulcers at 6, 12, 18 and 24 weeks. Results Kaplan-Maier analysis showed high pressure leads to higher proportion of healed venous leg ulcers, compared to moderate pressure, in patients aged ≥65 years (57.6% vs. 28%) and in patients <65 years (53.8% vs. 36%) (p < 0.05). Conclusion The study showed that higher compression pressure leads to higher proportions of venous leg ulcers healed, independent of age and could be safely preferred in older patients.

Keywords: Venous ulcers; compressive therapy; elderly; healing rate; sub-bandage pressure.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Age Factors
  • Aged
  • Compression Bandages*
  • Compressive Strength*
  • Disease-Free Survival
  • Female
  • Humans
  • Male
  • Middle Aged
  • Survival Rate
  • Varicose Ulcer / mortality*
  • Varicose Ulcer / physiopathology
  • Varicose Ulcer / therapy*