Two-Center Evaluation of Disinfectant Efficacy against Ebola Virus in Clinical and Laboratory Matrices

Emerg Infect Dis. 2018 Jan;24(1):135-139. doi: 10.3201/eid2401.170504.

Abstract

Ebola virus (EBOV) in body fluids poses risk for virus transmission. However, there are limited experimental data for such matrices on the disinfectant efficacy against EBOV. We evaluated the effectiveness of disinfectants against EBOV in blood on surfaces. Only 5% peracetic acid consistently reduced EBOV titers in dried blood to the assay limit of quantification.

Keywords: Ebola virus; bleach; clinical matrix; disinfectant efficacy; disinfection; filovirus; laboratory matrix; peracetic acid; two-center evaluation; viruses.

Publication types

  • Multicenter Study
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bleaching Agents / pharmacology
  • Cells, Cultured / virology
  • Disinfectants / pharmacology*
  • Dried Blood Spot Testing
  • Ebolavirus / drug effects*
  • Humans
  • Laboratories
  • Peracetic Acid / pharmacology

Substances

  • Bleaching Agents
  • Disinfectants
  • Peracetic Acid