Next-generation sequencing applications in clinical bacteriology

Yair Motro; Jacob Moran-Gilad

doi:10.1016/j.bdq.2017.10.002

Next-generation sequencing applications in clinical bacteriology

Biomol Detect Quantif. 2017 Oct 23:14:1-6. doi: 10.1016/j.bdq.2017.10.002. eCollection 2017 Dec.

Authors

Yair Motro¹, Jacob Moran-Gilad^{1

2

3}

Affiliations

¹ Department of Health System Management, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
² Public Health Services, Ministry of Health, Jerusalem, Israel.
³ ESCMID Study Group for Genomic and Molecular Diagnostics (ESGMD), Basel, Switzerland.

Abstract

With the rapid advances in next generation sequencing (NGS) technologies, clinical and public health microbiology laboratories are increasingly adopting NGS technology in their workflows into their existing diagnostic cycles. In this bacteriology focused review, we review aspects and considerations for applying NGS in the clinical microbiology settings, and highlight the impact of such implementation on the analytical and post-analytical stages of diagnosis.

Keywords: Applications; Clinical diagnostics; Clinical microbiology; Next generation sequencing; Public health; Workflow.

Publication types

Review