Three new 3,4-seco-cycloartane triterpenes from Gardenia sootepensis

Nat Prod Res. 2018 Oct;32(19):2338-2342. doi: 10.1080/14786419.2017.1413561. Epub 2017 Dec 18.

Abstract

The plants in the genus Gardenia (Rubiaceae) have long been used as traditional medicines in China. In this study, two new 3,4-seco-cycloartane triterpenes, sootepin J (1) and sootepin K (2), and a novel nor-3,4-seco-cycloartane triterpenes, sootepin L (3), together with two known compounds (4-5), were isolated from the methanolic extract of the leaves and twigs of Gardenia sootepensis. The structures of the new compounds were elucidated by combinations of 1D, 2D NMR experiments and HR-MS data, while the known compounds were identified by comparison of the NMR data with previously published data.

Keywords: Gardenia sootepensis; Rubiaceae; nor-3,4-seco-cycloartane; triterpenes.

MeSH terms

  • China
  • Gardenia / chemistry*
  • Molecular Structure
  • Plant Leaves / chemistry
  • Spectrum Analysis
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification*

Substances

  • Triterpenes
  • cycloartane