[Prolonged optic disc swelling in Kawasaki disease - A case report and literature review]

Nihon Rinsho Meneki Gakkai Kaishi. 2017;40(5):377-381. doi: 10.2177/jsci.40.377.
[Article in Japanese]

Abstract

Kawasaki disease (KD), an acute childhood panvasculitis, presents a variety of ocular complications as well as conjunctival injection among the principal symptoms. However, most pediatricians are unfamiliar with the ophthalmological complications of KD. A 2-year-old girl was referred to us from the ophthalmology department due to injected bulbar conjunctivae and optic disc swelling. She had familial exudative vitreoretinopathy as an underlying disease and the ocular findings had been made by chance while the patient was receiving an eye examination. Although she was afebrile at the time of her first medical interview, KD was diagnosed based on the presence of four of the principal symptoms including fever and dilatation of the coronary arteries. Intravenous immunoglobulin (IVIG) therapy was administered on Day 15 from the onset of fever. After IVIG administration, her laboratory test results showed rapid improvement but her optic disc swelling continued for six months. Eye complications in KD generally occur in the anterior segment, and recovery occurs within two months. Past reports have shown that in three of seven KD cases with optic disc involvement, optic disc swelling lasted over two months. This is the second case in which the condition lasted six months.

Keywords: Kawasaki disease; complication; eye involvement; optic disc swelling.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Child, Preschool
  • Conjunctiva / pathology
  • Female
  • Humans
  • Immunoglobulins, Intravenous / administration & dosage
  • Incidental Findings
  • Mucocutaneous Lymph Node Syndrome / complications*
  • Mucocutaneous Lymph Node Syndrome / therapy
  • Optic Disk / pathology*
  • Optic Nerve Diseases / etiology*
  • Optic Nerve Diseases / pathology*
  • Time Factors
  • Treatment Outcome
  • Vitreoretinopathy, Proliferative / complications
  • Vitreoretinopathy, Proliferative / genetics

Substances

  • Immunoglobulins, Intravenous