[Insulinoresistancy in Man: from mechanisms to nutritional interference]

Abstract

Obesity is presently regarded as the "the first non-infectious epidemic outbreak" in the history of Humanity. It is a multifactorial pathology, that contributes to the emergence of insulinoresistancy. Some obese individuals display an obesity qualified as metabolically sound, i.e., non-associated with metabolical anomalies. The present paper reviews the different possible mechanisms responsible for insulin-resistancy.