Exploring mechanochemistry to turn organic bio-relevant molecules into metal-organic frameworks: a short review

Beilstein J Org Chem. 2017 Nov 14:13:2416-2427. doi: 10.3762/bjoc.13.239. eCollection 2017.

Abstract

Mechanochemistry is a powerful and environmentally friendly synthetic technique successfully employed in different fields of synthetic chemistry. Application spans from organic to inorganic chemistry including the synthesis of coordination compounds. Metal-organic frameworks (MOFs) are a class of compounds with numerous applications, from which we highlight herein their application in the pharmaceutical field (BioMOFs), whose importance has been growing and is now assuming a relevant and promising domain. The need to find cleaner, greener and more energy and material-efficient synthetic procedures led to the use of mechanochemistry into the synthesis of BioMOFs.

Keywords: BioMOFs; drugs; green chemistry; mechanochemistry; organic based materials.

Publication types

  • Review