Objective: To preliminary assess the efficacy of DONG's extraordinary acupoints for the ovarian function of polycystic ovary syndrome.
Methods: Fifty-six patients were randomized into an acupuncture group and a western medication group. In the acupuncture group, the acupoints were Fuke, Huanchao, Tianhuang (Yinlingquan, SP 9), Renhuang (Sanyinjiao, SP 6), Guanyuan (CV 4), Zigong (EX-CA 1). The treatment was used twice a week for continuous 12 weeks. In the western medication group, patients were given diane-35 for 3 menstrual cycles, once a day for 21 days with 7 days between the two sessions. The ratio of luteinizing hormone/flitropin (LH/FSH) was taken as the primary index, while the secondary indices were serum testosterone (T), FSH, LH, body mass index (BMI), the condition of ovary and menstruation.
Results: ①After treatment, the ratio of LH/FSH declined in both the two groups (P<0.05, P<0.01). The decreasing values of the two groups were not significantly different (P>0.05). ②T, LH and BMI dropped in the two groups (P<0.05, P<0.01). The decreasing values of the three indices between the two groups were not significantly different (all P>0.05). ③The size of ovary did not change significantly after treatment in the two groups (both P>0.05), but the reduction degree of ovary size of the acupuncture group was larger than that of the western medication group (P<0.05). The ovary number of more than 10 foliiculi in single ovary in the acupuncture group reduced compared with that before treatment (P<0.05). The reduction degree of ovary number with the above feature was not significantly different between the two groups (P>0.05). ④The times and days of menstruation within 3 months increased significantly in the two groups (all P<0.01), without significance of different valves between the two groups (both P>0.05).
Conclusions: DONG's extraordinary acupoints could improve the ovarian function of polycystic ovary syndrome, whose effect is similar as diane-35.
Keywords: DONG's extraordinary acupoints; pilot trial; polycystic ovary syndrome; randomized controlled trial (RCT).