Non-cancer drug consumption during the early trajectory of lymphoma survivorship

Therapie. 2018 Sep;73(4):307-317. doi: 10.1016/j.therap.2017.10.007. Epub 2017 Nov 22.

Abstract

Purpose: This study explored the use of non-cancer drugs in lymphoma survivors during the early trajectory (0 to 2 years) of cancer survivorship and determined the factors that influenced this consumption.

Methods: Between January and March 2014, a cross-sectional survey was conducted to assess drug consumption in adult lymphoma survivors at the Toulouse University Hospital. This study was based on a questionnaire consisting of ten open questions related to medical prescription and/or self-medication occurring within the last 3 months.

Results: A total of 83/103 lymphoma survivors returned the questionnaire. This study showed that 91.6% of patients were drug consumers (about twice more than the general French population). Twenty percent of patients were treated with≥5 drugs. Overall drug consumption mainly concerned analgesics, anti-inflammatory drugs and psychotropics. The presence of comorbidity, urban residence and female gender were associated with overall drug consumption. Moreover, half of survivors required at least one self-medication. Finally, only seven survivors (8.4%) reported no use of any medication.

Conclusion: This study shows that, at least during the early trajectory of cancer survivorship, lymphoma patients are heavily treated with non-cancer drug therapy. This drug consumption profile may have serious implications in terms of safety, overall benefit and health economics.

Keywords: Behind-the-counter drug; Lymphoma; Prescription drugs; Psychotropic drugs; Survivor.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cross-Sectional Studies
  • Drug Utilization / statistics & numerical data*
  • Female
  • Humans
  • Lymphoma / drug therapy*
  • Male
  • Middle Aged
  • Pharmacoepidemiology
  • Prescription Drugs
  • Self Medication
  • Surveys and Questionnaires
  • Survivorship*

Substances

  • Prescription Drugs