Sleep-Disordered Breathing among Newborns with Myelomeningocele

Renée A Shellhaas; Payal V Kenia; Fauziya Hassan; John D E Barks; Niko Kaciroti; Ronald D Chervin

doi:10.1016/j.jpeds.2017.10.070

Sleep-Disordered Breathing among Newborns with Myelomeningocele

J Pediatr. 2018 Mar:194:244-247.e1. doi: 10.1016/j.jpeds.2017.10.070. Epub 2017 Dec 6.

Authors

Renée A Shellhaas¹, Payal V Kenia², Fauziya Hassan³, John D E Barks², Niko Kaciroti², Ronald D Chervin⁴

Affiliations

¹ Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI; Sleep Disorders Center, University of Michigan, Ann Arbor, MI. Electronic address: shellhaa@med.umich.edu.
² Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI.
³ Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI; Sleep Disorders Center, University of Michigan, Ann Arbor, MI.
⁴ Sleep Disorders Center, University of Michigan, Ann Arbor, MI; Department of Neurology, University of Michigan, Ann Arbor, MI.

Abstract

In a matched cohort study, we report that the apnea-hypopnea index is significantly higher in neonates with myelomeningocele (34 ± 22) compared with age-matched controls (19 ± 11; P = .021). Assessment of newborns with myelomeningocele for sleep-disordered breathing may facilitate early treatment; the impact on long-term neurodevelopment is unknown.

Keywords: central sleep apnea; neonatal; obstructive sleep apnea; polysomnography; spina bifida.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Cohort Studies
Female
Follow-Up Studies
Humans
Infant, Newborn
Male
Meningomyelocele / complications*
Polysomnography / methods
Sleep Apnea Syndromes / epidemiology
Sleep Apnea Syndromes / etiology*

Abstract

Publication types

MeSH terms

Grants and funding