Physiology of milk secretion

Best Pract Res Clin Endocrinol Metab. 2017 Aug;31(4):367-384. doi: 10.1016/j.beem.2017.10.008. Epub 2017 Oct 31.

Abstract

Milk is a unique and complete nutritive source for the mammal neonate, also providing immune protection and developmental signals. Lactation is a complex process, proper to the mother and child dyad, and including numerous variables ranging from psychological aspects to the secretory functioning of the mammary epithelial cells, all contributing to a successful breastfeeding. This review gives an integrated overview of the physiology of lactation with a particular focus on cellular and molecular mechanisms involved in milk product secretion and their regulations.

Keywords: breastfeeding; lactation; mammary epithelial cell; mammary gland; milk; secretion.

Publication types

  • Review

MeSH terms

  • Animals
  • Animals, Newborn
  • Breast / metabolism*
  • Breast Feeding / psychology
  • Epithelial Cells / metabolism
  • Female
  • Humans
  • Infant, Newborn
  • Lactation / physiology*
  • Lactation / psychology
  • Mammary Glands, Animal / metabolism*
  • Milk / metabolism*