Pancreatic cancer is a poor prognostic tumor and about 20% of patients are eligible for surgical resection at the time of diagnosis. Recently, minimally invasive procedures have provided promising results as a therapeutic option for locally advanced unresectable pancreatic cancer. In particular, high-intensity focused ultrasound is an emerging noninvasive thermally ablative procedure that may have a dominant role in the future. Although the clinical applications of minimally invasive therapies to pancreatic cancers are still in their infancy, the results at present are promising.
Keywords: Cryotherapy; High-intensity focused ultrasound; Irreversible electroporation; Microwave ablation; Minimally invasive therapies; Pancreatic cancer; Radiofrequency ablation.
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