Treatment of adult acute myeloid leukemia

Duodecim. 2016;132(16):1465-73.

Abstract

The aim of this study was to analyze the treatment results of 180 adult AML patients treated at Turku University Hospital from 2002 to 2012. 124 patients received intensive therapy according to the protocol of the Finnish Leukemia Group. 86% of them achieved remission. 46 patients underwent allogeneic stem cell transplantation which was beneficial for high and intermediate risk disease. 60 - 70% of patients under 60 years old can be cured. The genetic profile of the disease, patient age and treatment response had a significant impact on survival. Our treatment results are comparable with data in literature.

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Female
  • Finland
  • Humans
  • Leukemia, Myeloid, Acute / therapy*
  • Male
  • Middle Aged
  • Remission Induction
  • Stem Cell Transplantation
  • Survival Rate
  • Treatment Outcome